NEW YORK — The latest on developments in financial markets (all times local):9:35 a.m.U.S. stocks are opening higher as the market wraps up another strong week.U.S. industrial production grew more than expected in December and technology and industrials made rose Friday. Microsoft rose 1.2 per cent and Deere rose 1.3 per cent.Transportation and logistics company J.B. Hunt jumped 6.1 per cent after its fourth-quarter report.Electric car maker Tesla fell 6.3 per cent after saying it will cut 7 per cent of its jobs.Timberland maker VF jumped 13.7 per cent after raising its annual forecasts.The S&P 500 index climbed 17 points, or 0.7 per cent, to 2,653.The Dow Jones Industrial Average rose 163 points, or 0.7 per cent, to 24,533. The Nasdaq composite added 47 points, or 0.7 per cent, to 7,131.The Associated Press
“This Convention can make a real difference to the quality of life of millions of people around the world,” Mr. Annan said in a message today to the ad hoc committee in Vienna drawing up the treaty delivered by Antonio Maria Costa, Executive Director of the UN Office on Drugs and Crime (UNODC).”It is particularly heartening that you were able to complete this process in less than two years,” he said of the Convention on Corruption, which will be put to a ministerial signing conference in Merida, Mexico, from 9 to 11 December.Once adopted, the treaty will enhance cooperation between governments and help standardize the way in which individual countries deal with corruption in their national legislation.The requirement for Member States to return assets obtained through bribery and embezzlement to the country of origin represents a new fundamental principle in international treaties. In a number of countries, corruption has led to the depletion of national wealth. Some of those countries, whose former dictators have stolen hundreds of millions, or even billions, of dollars, have made a great contribution to the search for new rules, including the Philippines and Nigeria.Preventive measures in the Convention include norms of conduct for public officials, greater transparency based on public access to information on government businesses, and stricter procurement regulations and measures against money laundering.
“All Member States are required to take the necessary measures to prevent the direct or indirect supply, sale or transfer of weapons and military equipment to designated individuals and entities, which includes Al-Shabaab,” the Council wrote in the resolution.The text, which extends the ban through 25 October, cites reports by the Somalia and Eritrea Monitoring Group (SEMG) that arms have been diverted and expresses “serious concern” that the requirements for a suspension of the embargo “have not been fully met.”The text also cites the 15 Members “condemning flows of weapons and ammunition supplies to and through Somalia in violation of the arms embargo on Somalia, as well as the destabilizing accumulation and misuse of such weapons, as a serious threat to peace and stability in the region.”In March 2013, the partially lifted the weapons ban for one year to boost the Government’s capacity to protect areas recovered from the militant group Al-Shabaab and defend against fresh attempts by such groups to destabilize the country.It decided that the arms embargo, originally imposed in 1992, would not apply to arms or equipment sold or supplied solely for the development of the Government’s security forces, but it kept its restrictions in place on heavy weapons, such as surface-to-air missiles.It also required the Government to notify the Council’s sanctions committee at least five days in advance of any such deliveries and provide details of the transactions. Alternately, Member States delivering assistance may make the notification after informing the Government of its intentions in that regard.Under requirements set forth in today’s text, all transactions are required to include details of the manufacturer and supplier of the arms and ammunition, a description of the arms and ammunition including the type, calibre and quantity, proposed date and place of delivery, and all relevant information concerning their storage.
Share22 Tweet Email THE CENTRAL AFRICAN Republic (CAR) said today that a diplomatic passport tennis star Boris Becker claims entitles him to immunity in bankruptcy proceedings in Britain “is a fake”.“The diplomatic passport that he has is a fake,” foreign ministry chief of staff Cherubin Mologbama told AFP.The document’s serial number corresponded to one of a batch of “new passports that were stolen in 2014,” he said.In addition, the passport, a copy of which has been seen by AFP, and bears the date of 19 March 2018 does not carry the signature or the stamp of the foreign minister, Charles Armel Doubane, Mologbama said.On Friday, lawyers for Germany’s three-time Wimbledon champion lodged a claim in the High Court in Britain saying that he had been appointed a sports attaché for the CAR to the European Union (EU) in April.This, they argued, granted him immunity under the 1961 Vienna Diplomatic Convention on Diplomatic Relations from bankruptcy proceedings over failure to pay a long-standing debt.“Becker’s job profile does not exist” in the CAR’s records, Mologbama said.Furthermore, the passport says that Becker’s diplomatic function is “financial charge de mission”, a role that “has nothing to do with sporting questions,” he noted.In April, the 50-year-old former tennis star had tweeted a picture of himself shaking hands with CAR President Faustin-Archange Touadera at a meeting in Brussels.Becker shook up the tennis world at Wimbledon in 1985 when, as an unseeded player, he became the then youngest-ever male Grand Slam champion at the age of 17, defending the trophy the following year.The German went on to enjoy a glittering career and amassed more than €21 million in prize money.Shadowy reputationThe CAR is one of the poorest countries in the world, ranking at the very bottom of the 188 nations in the UN Development Programme’s 2016 Human Development Index.Landlocked, rich in gold, diamonds, oil and uranium, the country of 4.6 million people has been chronically unstable since it gained independence from France in 1960.Presidents have traditionally been surrounded by “sleazy courtesans” and “dodgy counsellors who talk loud,” French writer Jean-Pierre Tuquoi wrote in a book published last year.Its modern history has been studded with coups, foreign mercenaries, assassination attempts, shadowy business deals and improbable figures, he says.They include Jean-Bedel Bokassa, a former army corporal and fan of Napoleon who became president, then president for life – and finally declared himself emperor before being ousted by France in 1979 after a massacre of school children.One of his successors, Francois Bozize, was named in a lawsuit filed in France in 2015 by the CAR government, which said that during his tenure, “numerous advisors and relatives… benefitted from passports of convenience” in exchange for money.These including a Kazakh opposition figure, Mukhtar Abiazov, a female advisor to former Libyan dictator Moamer Kadhafi, and an Israeli businessman, according to the suit filed by the CAR’s attorney, William Bourdon.Bozize was overthrown in 2013 by a mainly Muslim rebel alliance, the Seleka. His elected successor, Faustin-Archange Touadera, has effective rule over only a fraction of the country as most of it is in the hands of militias.Poor governance and a tradition of graft make for a toxic mixture, says Thierry Vircoulon, a CAR specialist at the French Institute for International Relations (IFRI).“Given the authorities’ extreme weakness and corruptibility, crooks and conmen of every stripe always find a way to gain access to the president and make money,” he says. “This country is perfect for business pirates.”- © AFP 2018 Tuesday 19 Jun 2018, 5:42 PM Boris Becker’s diplomatic passport is ‘fake’ says Central Africa Republic The document’s serial number corresponded to one of a batch of new passports that were stolen in 2014. Short URL Jun 19th 2018, 5:43 PM Tweet thisShare on FacebookEmail this article By AFP 48,983 Views Boris Becker Boris Becker https://jrnl.ie/4079945 21 Comments
Facebook, requête la plus populaire sur GoogleGoogle a publié sa liste de mots-clés les plus recherchés sur son moteur de recherche cette année en France. Comme en 2009, c’est Facebook qui se place en tête du palmarès Zeitgeist, devant leboncoin.fr. Google a publié sa liste très attendue des mots-clés les plus recherchés sur son moteur de recherche. La palme revient à Facebook qui devance de peu le site de ventes d’occasion leboncoin.fr. Concernant la vente en ligne, c’est La Redoute qui domine. Les sites Internet eBay et CDiscount sont les grands perdants dans ce domaine. Pour les actualités, le journal en ligne du Monde arrive à détrôner TF1, Le Figaro et Le Parisien. L’application Chatroulette enregistre la plus grande progression et, nouveauté cette année, dans le classement des personnalités : c’est le jeune chanteur Justin Bieber qui arrive en tête, même si Super Nanny n’a pas été oubliée. Le 13 décembre 2010 à 13:13 • Emmanuel Perrin
NASA Says 2 Asteroids Will Safely Fly By Earth This WeekendScientists Discover Possible Interstellar Visitor Stay on target NASA is headed to space on Pi Day: A new U.S.-Russian crew will launch to the International Space Station (ISS) today and begin their six-month stay at the orbiting laboratory.The Expedition 59 liftoff, which will be live-streamed on NASA TV, is scheduled for 3:14 p.m. EST and will take place at the Baikonur Cosmodrome in Kazakhstan, Space.com reported. NASA will start a webcast at 2 p.m. EST, which will discuss the Expedition 59 mission and broadcast the crew’s takeoff.The Expedition 59 Soyuz rocket, mission management, and members of the media have been blessed. Astronauts @Astro_Christina, @AstroHague and cosmonaut Alexey Ovchinin are set to launch later today (Eastern Time.) More images: https://t.co/oHGmm09if6 pic.twitter.com/jhQ1xnxDup— NASA HQ PHOTO (@nasahqphoto) March 14, 2019The three individuals traveling to the ISS include NASA astronauts Nick Hague and Christina Koch, and Russian cosmonaut Alexey Ovchinin. In October, Hague and Oychinin were scheduled to go to the ISS, however, their rocket experienced a booster issue that resulted in an emergency launch abort and sent them back to the ground.What’s the perfect time to launch a rocket on #PiDay? 3:14, of course! Tune in starting at 2pm ET to see three humans launch to the @Space_Station for a six-and-a-half month mission. Details: https://t.co/thyIGe26bG pic.twitter.com/rxdbCn7tJv— NASA (@NASA) March 14, 2019Following the launch, the Expedition 59 astronauts will spend roughly six hours traveling to the ISS, and once they arrive there, they will join NASA astronaut Anne McClain, Canadian astronaut David Saint-Jacques, and Russian cosmonaut Oleg Kononenko, who have been at the ISS since December.The incoming astronauts will be part of some exciting events coming up at the ISS: Hague and Koch will each have a spacewalk at the end of the month. On March 29, Koch and McClain will participate in the first-ever female astronaut spacewalk, which will be a major milestone for women in the space industry.More on Geek.com:NASA Boss Says First Person on Mars Will ‘Likely Be a Woman’ NASA Makes Ultima Thule ‘Pop’ in Artsy 3D ImagesNASA Spots ‘Hopping’ Liquid Water on Moon’s Surface
Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 28 Aug 2015 (by Shorrell Dames, @magneticmedia1) – Flight operations suspended in the TCI due to TS Erika; the TCIAA announced on Thursday that flight operations at Providenciales International Airport will be suspended from 6 p.m. Friday 28th August to 12 p.m. Sunday 30th August. TS Erika is expected to have sustained winds at 46knts with higher gusts that when paired with Erika’s torrential rain would inevitably result in adverse conditions.Airport Authority’s CEO, John Smith says that, the TCIAA “remains committed to serving the flying public in the safest manner and are taking every precaution to ensure this.”The Airports Authority is closely monitoring the storms progress and will issue updated reports as warranted, board and management of the Airports Authority apologizes to the public for any inconvenience caused. Recommended for you Facebook Twitter Google+LinkedInPinterestWhatsApp Related Items:john smith, provo international airport, slosure, Tciaa, tropical storm erika Airports Authority reveals sabotage at South Caicos Airport Former Premier says PNP left plan for Salt Cay airport, but there is no evidence of the claim Airports Authority commanded to protect South Caicos airport by airline
READING, MA — Choose your actions wisely, use your gifts to help others, and be sure to appreciate the joy in everyday life was the advice the 142 graduates of Austin Preparatory School received during Commencement Exercises on Saturday, May 20th.Their “joy” began at Baccalaureate Mass on Friday, May 19th, as the graduates, parents, faculty and leadership of Austin Prep, when asked by Fr. Ray Dlugos to “show your joy,” responded with thunderous applause and cheers. Fr. Dlugos is Vice President of Mission and Ministry at Merrimack College and an Austin Prep Trustee.Headmaster James Hickey, Ph.D. P’22, ’23, ’24 learned the same valuable lesson about joy from his grandmother.“Whatever you do make sure to find or – even better – create fun, and joy will certainly follow,” Dr. Hickey said. “Be intentional about it, make time for it, otherwise ‘life’ will get in the way of living a ‘happy life.’In addition to technical skills, every person has “Human to Human,” or “Heart to Heart” skills which are more important, as those skills define us, Mrs. Barbara Marchetti, the Graduation Keynote Speaker, told the graduates.“The majority of hiring decisions lean toward the ‘Human to Human,’ ” she said. “It is the ultimate tie breaker. If someone is deficient with a technical tool but makes up for it with his/her ‘Human to Human’ tools – guess who’s selected?”Mrs. Marchetti is the founder and president of C-suite Corporation, a retained executive search firm which specializes in the talent acquisition of executives from the C-suite down to the director levels. She has more than 30 years of experience impacting the executive infrastructure of business and industry, and is an internationally known business strategist, trainer and public speaker who has worked with hundreds of companies and thousands of executives globally. Mrs. Marchetti is an Austin Prep Trustee and parent of an alumnus from the Class of 2017.Her sentiment was echoed by the Class of 2018 Valedictorian Caitlyn Leonard of Peabody, who remarked that as adults they should choose their actions carefully.“We will be defined in our everyday actions –– and those actions we make are our choice,” Caitlyn said. “So, will we choose to be defined by our open hearts? Our service to our country or community? Our love for our family and friends? Our hard work and determination? Our commitment to our faith? As we walk through those doors, we each have a choice, but as Austin Prep graduates I know the choice we will all make.”The Class of 2018 has already started implementing many of the ‘Human to Human’ tools learned during their years at Austin Prep to help others and live a life filled with joy.“Take the pen and write your own story,” Bridget Kelley of Melrose, Class of 2018 Salutatorian, told her fellow graduates. “Continue to make it a story of kindness, of spirit, of dedication, of acceptance, and of a love for life. I think that we as a class have already changed the world, because you have changed me, and we have changed each other, for the better.”All 142 graduates were accepted to numerous four-year colleges and universities.Congratulations to the following Wilmington studentsKatelyn Ardito will attend Saint Anselm College in the fall.Dylan Arnold will attend Xavier University in the fall.Joshua Bartnicki will attend Northeastern University in the fall. He received the Charles and Helen McLaughlin Medal for Leadership and Determination to Excel – Austin Prep’s highest award – as well as the Medal for Mathematics and the Medal for Physical Science.Thomas Burnham will attend Tufts University in the fall. He received the Medal for History.Heeweon Hwang will attend the University of Washington in the fall.Ellen Klucznik will attend Lehigh University in the fall.Logan MacDonald will attend Babson College in the fall.Phillip Marchese will attend Merrimack College in the fall.Kristen Olson will attend the University of Massachusetts Amherst in the fall.Megan Olson will attend Stonehill College in the fall.Lindsey Rosania will attend Sacred Heart University in the fall.Kaylee Todisco will attend Saint Joseph’s College, Maine in the fall.Yiming Xing will attend Trinity College in the fall.(NOTE: The above press release is from Austin Prep.):Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip?Share this:TwitterFacebookLike this:Like Loading… RelatedSTUDENT SPOTLIGHT: 5 Wilmington Students Graduate From Austin PrepIn “Education”7 Wilmington Students Graduate From Austin PrepIn “Education”Austin Prep Announces Commencement Speaker For 2017 GraduationIn “Education”
Governor Parnell signs HB 301, which eases the burdens on families for required autopsies. L to R: Alaska Medical Examiner Dr. Gary Zientek, Rep. Bob Herron, Governor Sean Parnell, YKHC President and CEO Dan Winkelman, and Senator Lyman Hoffman. (Photo by Dean Swope, KYUK – Bethel)Governor Sean Parnell was in Bethel Thursday to sign a bill intended to help rural families navigate the process of having an autopsy done hundreds of miles away in Anchorage.Download AudioWhen someone in western Alaska dies in suspicious or unusual circumstances, the state is required to conduct an autopsy or exam in Anchorage. Sometimes in that time of stress, family members are making decisions without good information. In a packed room of regional leaders at the Yukon Kuskokwim Health Corporation Thursday, Governor Parnell signed a bill into law intended to make that stressful time easier.“This is about dignity and respect for our lost loved ones, as well as the dignity and respect of the families that are involved,” said Parnell.The bill makes explicit that families can choose to have the body returned directly to them, instead of a funeral home. Bethel Representative Bob Herron sponsored the bill.“It’s hard on the family because they want closure, they want it done right. And in the past, it’s to no fault of anybody, but the state appeared to be promoting the funeral home business,” said Herron.Part of that was the documentation for families, which has been changed. Supporters cite stories of people getting stuck with large funeral home bills they couldn’t pay. That’s led to some funeral homes holding the body hostage until they get paid.Nicholas Hoover is the Social Services Director for Association of Village Council Presidents and works with families in need. He says good communication hasn’t always happened in the past and points to a recent 7-thousand dollar funeral home bill.“If a family isn’t prepared, they can tack on services like embalming, it’s toxic, and it’s not traditional custom to have a body embalmed. Cosmetics is another…traditionally the family is the one who dresses the body and prepares it for a funeral,” said Hoover.The law also allows for the possibility of some exams to be done outside of urban areas in a hub like Bethel with video equipment. That could cut down on the approximately 900 cases the medical examiners see annually.Dr. Gary Zientek is Alaska’s Chief Medical Examiner. He says there are no plans yet to establish a rural examination program and the requirements for a facility and training are steep.“…Photographs and fingerprints, we have to do a lot of documentation it would be a lot of training. It would probably be possible, but it requires a lot of work before we do that,” said Zientek.The law would pay for embalming if required by an air carrier and could return the body to places besides the exact location of the death. The Governor also signed resolutions in support of Alaska’s role in national arctic policy and of Recover Alaska’s efforts to reduce excessive alcohol consumption. He spoke at the Bethel Chamber of Commerce.
Students and teachers of History department of Dhaka University form a human chain at the foot of Aparajeyo Bangla on the campus on Wednesday, 18 July 2018. Photo: UNBStudents and teachers of History department of Dhaka University on Wednesday formed a human chain at the foot of Aparajeyo Bangla on the campus protesting the assault on a student of the department.They also demanded security of the students on the campus and exemplary punishment of the attackers, reports UNB.Tanjir Hossain Sarker, a master’s student of the department, was among teachers and students who were allegedly assaulted by the Bangladesh Chhatra League (BCL) men recently while protesting the arrest of quota reform activists.Chhatra League is the student wing of ruling Bangladesh Awami League (AL).Condemning the assault as well as the passive role played by the university authorities, Mehedi Hasan, a student of the department said, “It is the responsibility of the university authority to ensure the security of its students. But, they failed to do so.”“Now, people in the country are being attacked for demanding their rights. When people stand to protest the attack carried out on them, they too become victims.”“If democracy is there in the country why people cannot stand for their rights?” he added.While speaking at the human chain, professor Mohammad Abul Kawser of the department urged the government to take necessary steps to consider the logical demand of the students.
Deep-Diving Exosuit The team has scheduled a test run of the suit this summer at a site called the Canyons off the coast of Rhode Island. If all goes well, plans for exploring the Antikythera wreck can proceed, paving the way for a whole new way to explore undersea wrecks from virtually any era. More information: The Exosuit: www.amnh.org/exhibitions/past- … ibitions/the-exosuitvia Newscientist (Phys.org) —Marine archeologists with the Hellenic Ministry of Culture research program (with support from the Woods Hole Oceanographic Institution) are planning to explore the ancient Greek Antikythera wreck in the Agean Sea, using an exosuit developed by Nuytco Research—originally for use in helping workers in New York’s water treatment facilities. The iron-man looking exosuit allows a diver to descend to 1000 feet for hours at a time without need for decompressing upon returning to the surface. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Credit: American Museum of Natural History Credit: American Museum of Natural History The Antikythera was discovered by divers in 1900—attempts to explore the wreck resulted in recovery of many artifacts, mostly famously, one that is known as the Antikythera mechanism—now referred to as the world’s oldest computer. But it also led to injury and death due to the extreme depth (120 meters). Subsequent attempts more recently have led to more discoveries, but time constraints have prevented a thorough study of the wreck. Wearing the exosuit, the researchers hope will not only allow for mapping the wreck, but for discovery of more artifacts, some perhaps as interesting as the Antikythera mechanism.The suit, which is essentially a body submarine, allows for both arm and leg movements, courtesy of multiple patented rotary joints. It also has 1.6 horsepower thrusters that are activated by the “pilot” via pads inside the boots. It’s made of mostly aluminum, and weighs 530 pounds. The hands are claw-like, which has meant many hours of training in pools for the research team. The suit also has external LED lights and cameras, an oxygen replenishment system and a tether to the surface with a fiber optic gigabit Ethernet that allows for two-way communications, a live video feed, and monitoring of the suit and its wearer. In the event of an emergency, the suit has backup batteries and systems to maintain life support—if necessary, the four man crew up top can take over control of the suit to bring the diver out of harm’s way. © 2014 Tech Xplore Citation: Researchers to use exosuit to explore ancient Antikythera wreck (2014, June 5) retrieved 18 August 2019 from https://phys.org/news/2014-06-exosuit-explore-ancient-antikythera.html Archaeologists return to ancient Greek ‘computer’ wreck site: official Explore further
Controlled nucleation is essential for robust self-assembly. (A) An example 86-strand DNA-brick structure and (B) its associated connectivity graph. (C) Incidental interactions between dangling ends, shown in orange, lead to incorrect associations between fragments. Credit: (c) 2015 PNAS, DOI: 10.1073/pnas.1502210112 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. (Phys.org)—DNA bricks are an odd phenomenon. They are nanostructures built from synthetic, single-strand DNA that self-assemble into 3D structures. Several years ago, researchers at Wyss Institute at Harvard demonstrated the self-assembly of designed 3D structures made from 1,000 “bricks” that fit together like molecular Legos. One of the curiosities about these DNA bricks is why this complex self-assembly process works so well. Journal information: Proceedings of the National Academy of Sciences In an effort to uncover the nuances of DNA brick self-assembly, William M. Jacobs, Aleks Reinhardt, and Daan Frenkel from the University of Cambridge conducted theoretical studies to understand what drives the assembly process. Their studies reveal how temperature, kinetics, coordination number, and bond energies, contribute to the unique behavior of DNA brick self-assembly, and while it is a nucleated process, it does not behave according to classical nucleation theory. Their work appears in the Proceedings of the National Academy of Sciences.In order to optimize DNA brick assembly, Jacobs, et al. wanted to investigate whether these systems had a nucleation barrier. In classic nucleation theory (CNT), the nucleation barrier is the energy cost for making an ordered structure, such as a crystal. This energy barrier must be overcome before a compound can settle into its equilibrium structure. The authors found that DNA brick assembly does have a nucleation barrier, but, unlike CNT, this barrier is determined by the way the bricks are connected in the target structure. They identified several factors that contribute to this non-classical behavior.DNA bricks are designed to assemble in particular ways by matching certain sections of a DNA strand with a complimentary section. These designed interactions need to be stronger than incidental interactions. They found that there is a critical number of DNA strands that must be assembled to promote the formation of the target structure, meaning that the the nucleation barrier is a consequence of the number of subunits that must be assembled.Additionally, DNA-bricks have a certain temperature range at which the nucleation barrier is overcome, but over which the free energy of the final structure is higher than the initial monomers. This deviates from CNT which predicts that a nucleus with more than the critical number of DNA strands will assemble into the complete structure. This difference is due to DNA bricks forming stable intermediate structures. Experimentally, this means that self-assembly occurs in a narrow temperature range in which nucleation begins at a high temperature, and as the structure is gradually cooled, the target structure is favored.In prior studies, the maximum number of bonds made by each brick in the interior of a structure was four, but it is possible to have different coordination numbers. The question was whether the coordination number affected the nucleation barrier, and whether four bonds were necessary. It turns out that DNA brick self-assembly works well because each subunit makes only a small number of bonds. When the authors tested higher coordination numbers, they found that the system behaved analogously to CNT.Finally, Jacobs et al. found that contrary to theories that homogenous bond energies would decrease the number of errors during DNA brick assembly, it is the diversity in bond energies that contributes to enhanced kinetics of DNA brick self-assembly. This was likely due to stabilizing unstable intermediate structures.Jacobs, et al. have identified several key features that aid in understanding why DNA brick self-assembly works as well as it does. Features such as ramping down the temperature and optimizing the coordination number explain why there are so few errors in the self-assembly process. And, their discovery that heterogeneous bond energies promote target molecule formation is a practical place where researchers can improve yields and decrease errors in DNA brick assembly. More information: “Rational design of self-assembly pathways for complex multicomponent structures” PNAS, DOI: 10.1073/pnas.1502210112AbstractThe field of complex self-assembly is moving toward the design of multiparticle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such “addressable complexity,” we need to understand the factors that optimize the yield and the kinetics of self-assembly. Here we use a simple theoretical method to explain the key features responsible for the unexpected success of DNA-brick experiments, which are currently the only demonstration of reliable self-assembly with such a large number of components. Simulations confirm that our theory accurately predicts the narrow temperature window in which error-free assembly can occur. Even more strikingly, our theory predicts that correct assembly of the complete structure may require a time-dependent experimental protocol. Furthermore, we predict that low coordination numbers result in nonclassical nucleation behavior, which we find to be essential for achieving optimal nucleation kinetics under mild growth conditions. We also show that, rather surprisingly, the use of heterogeneous bond energies improves the nucleation kinetics and in fact appears to be necessary for assembling certain intricate 3D structures. This observation makes it possible to sculpt nucleation pathways by tuning the distribution of interaction strengths. These insights not only suggest how to improve the design of structures based on DNA bricks, but also point the way toward the creation of a much wider class of chemical or colloidal structures with addressable complexity. Citation: General principles to explain DNA brick self-assembly (2015, May 19) retrieved 18 August 2019 from https://phys.org/news/2015-05-principles-dna-brick-self-assembly.html © 2015 Phys.org Crystallizing the DNA nanotechnology dream: Scientists have designed the first large DNA crystals Explore further
The 20th edition of Delhi Book Fair and 16th Stationery and Office Automation Fair at Pragati Maidan ended on 31 August. The last day of the event featured award giving ceremony by Rita Menon, Chairperson and Managing Director, India Trade Promotion Organisation (ITPO) for Excellence in Display.Awards were presented in different categories comprising Hindi, Regional and English languages. In Hindi language category, Prabhat Prakashan won the gold trophy, Kitabghar Prakashan won silver and Hindi Book Centre won bronze trophy while in the English language category, MBD Group, Full Marks Pvt. Ltd. and Amity University Press won the gold, silver and bronze trophies, respectively. Also Read – ‘Playing Jojo was emotionally exhausting’National Book Trust bagged the gold trophy and Sahitya Akademi won the silver trophy in the Regional language categories. Ballarpur Industries Limited bagged the gold trophy and Paper Theatre and GSC Glass Ltd. received the silver and bronze trophies, respectively, for Excellence in Display in the Stationery and Office Automation Fair. The event also witnessed a workshop on book review Let’s Review a Book and an interactive session-cum workshop with an illustrator for school children on 29 August organised by National Centre for Children’s Literature, a wing of National Book Trust. Also Read – Leslie doing new comedy special with NetflixThe programme was divided into two sessions. The first session on book review was conducted by Nandini Sahu, Associate Professor of English, IGNOU and creative writer. The second session was on illustration was conducted by Subir Roy, renowned illustrator and Art Director at Children’s Book Trust.While giving details on how to write a book review, Sahu said ‘The role of reviewer is very important as the reviewer tells the reader what the book is all about. Since the reviewer has the freedom to write about the book, his mind should be open and should not have negative approach towards the writer.’ In the second session, Roy gave an insight into designing a cover of the book. He informed children about the young Indian artistes who have won several awards at international level. Roy shared his experience as an illustrator and gave tips to children to draw good illustrations.More than 150 children from various schools of Delhi and NCR including DAV Public School Paschim Enclave, DAV Public School Shreshtha Vihar, Ahlcon Public School, Mayur Vihar, Shraddha Public School, Faridabad participated in this programme.The best twenty students in the workshop were given away awards and certificates. The next edition of the fair will be organised from 29 August to 6 September, 2015.
CTM recognised as one of Australia’s most innovativeCorporate Travel Management (CTM; ASX CTD) has again been recognised as one of Australia’s most innovative companies, for its ongoing commitment to delivering innovation in its business model and service offering.CTM was ranked 37th on the AFR Most Innovative Companies List, which was announced at last night’s gala, in Sydney.This is the second consecutive year the company has been recognised for its innovation practices, having made the prestigious list in 2015 as the only travel company in the top 50.CTM’s CEO Australia & New Zealand and Global COO Laura Ruffles said the award recognises a team dedicated to service excellence, who constantly strive to innovate in their delivery of new services that challenge and improve the status quo.“The award is a testament to our dedicated team who work tirelessly behind the scenes to ensure CTM continues to add value to clients through its global network, industry-leading software and client offering,” she said.Ms Ruffles said as millennials become larger stakeholders in company decision-making processes, technology is becoming increasingly integral to staying competitive and winning new business.“We’re taking corporate travel technology to new heights both here in Australia and across the globe, with the delivery of tools which utilise big data and predictive technology to better understand and deliver on the needs of corporate travellers” she said.“This year we’ve delivered our clients a ground breaking new online booking tool which consumerises the process of booking corporate travel, and the first native mobile booking app built in Australia. Not only does this put the user ‘front and centre’ of the booking experience, it brings a new level of innovation, speed and agility to the corporate travel technology landscape.”CTM provides travel management solutions to some of Australia’s biggest companies and recently.partnered with Coles to deliver the technology solution behind flybuys travel which allows members to earn and burn flybuys points when booking their leisure travel.Finalists for the AFR awards are selected by industry experts, before the winners are selected by a team of Inventium analysts.About CTM CTM is an award-winning provider of innovative and cost-effective travel management solutions to the corporate market. Its proven business strategy combines personalised service-excellence with client-facing technology solutions to deliver a return-on-investment to clients.Headquartered in Australia, the company employs over 2,200 FTE staff globally and services clients in 82 countries.Source = Corporate Travel Management
The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Top Stories Each brings something to the table, with perhaps Niklas having the most raw ability. But it is Carlson, at 6-foot-5 and 248 pounds, who presents one of the most intriguing packages, given that he can be useful both as a blocker and a receiver.“We’re asked to do a lot of different things,” he said after a minicamp practice Tuesday. “It’s difficult, it’s challenging. Mentally it’s not easy, but it’s fun. We’ve got a good group of tight ends; I think we can do a lot of different things on the field.”Housler is known as more of a receiver who, entering his fourth season, may be facing a bit of a “make or break” year. Ballard is much like Carlson in that he’s shown potential but struggled with injuries. Niklas, a second-round pick, has struggled to stay healthy throughout the offseason, which may place him behind the veterans, while Hardy and Fells are just hoping to stick.All could find a spot with the team, though it’s not likely each will be on the roster when the season begins. The competition is ongoing, but there’s a reason the team signed Carlson to a two-year, $4 million contract in early March. TEMPE, Ariz. — Bruce Arians’ offense requires a tight end who can both block and catch. Historically that has not been something the Arizona Cardinals have had, though the belief is that has changed.“There’s great competition; that’s an NFL room right now,” Arians said following an OTA practice last week. That room consists of veterans Rob Housler, Jake Ballard and John Carlson, along with younger players Troy Niklas, Darren Fells and Andre Hardy. And so far, he has done nothing to make the team regret that decision.“John has done a really, really good job,” Arians said Tuesday after the team’s first minicamp. “First of all, he’s extremely bright — he picked up the system extremely quick. He plays full speed all the time and has got outstanding hands. His issue in the past has been he’s not an overwhelming blocker, but he’s more than adequate.”Though injuries caused much of his luster to wear off, it was just five years ago when Carlson caught 51 passes for 574 yards and seven touchdowns as a member of the Seattle Seahawks. He also spent time with the Minnesota Vikings, though his career there was limited due to various ailments. But he’s healthy right now, adding that the goal is to continue feeling that way. “We all deal with injuries, I’ve dealt with it in the past,” he said. “I’m not thinking about that. I’m thinking about doing what I can to prepare my body physically right now to mentally understand this offense and do the things I need to do on the field.”His ability to do so could go a long way toward determining whom Arians turns to at the position. As of now there is no clear-cut starter, meaning the job is very much up for grabs. Derrick Hall satisfied with D-backs’ buying and selling Comments Share Former Cardinals kicker Phil Dawson retires “We’ve got six guys in the position group,” Carlson said when asked if it’s a friendly competition. “Every team I’ve been on has been, it’s always competitive — we all want a job, obviously, who doesn’t? But at the same time, we’re supporting and doing everything we can to be as good as we can be.” – / 11 Grace expects Greinke trade to have emotional impact
PARK CITY, Utah — Believe it or not, Hollywood executives told Dwayne Johnson “no thanks” when he pitched his latest movie.It was an unusual rejection for the industry’s reigning box office champion, whose “Jumanji” reboot in 2017 made nearly $1 billion worldwide. And so before he trades insults with Jason Statham in “Hobbs & Shaw” or straps in for the Disney’s “Jungle Cruise,” the artist forever known as The Rock put on his independent film producer hat and went outside the traditional studio system to make “Fighting With My Family.”His Seven Bucks Productions found financing through WWE Studios and Britain’s Film4 to make the scrappy, relatively low-budget comedy inspired by WWE wrestler Paige’s life story. Johnson makes a cameo appearance.Ryan Pearson, The Associated Press AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by Ryan Pearson, The Associated Press Posted Feb 22, 2019 8:13 am PDT Dwayne Johnson goes indie with ‘Fighting With My Family’
Two men were remanded for four days by Paphos district court on Monday for being involved in a knife fight.Police said that a 25-year-old man and a 27-year-old man were involved in a fight which ended in a stabbing near the village square in Chlorakas.Both men were injured in the fight which police said appeared to be over family differences.The two men were taken to the A&E department of Paphos general hospital, where on duty doctors said they were not seriously injured. You May LikeEternally SunnyWhen You Realize What This Is Really For Your Jaw Will DropEternally SunnyUndoOceandrawThe One WD40 Trick Everyone Should Know AboutOceandrawUndoNutrition Expert7 Arthritis And Cancer Causing Foods You Might Be Eating DailyNutrition ExpertUndo Rouhani hopes British PM Johnson’s “familiarity” with Iran will help improve relationsUndoLED-lighting the way by 2020UndoGreece to overturn law that made universities no-go zone for policeUndoby Taboolaby Taboola
The Cypriot research vessel that was harassed by a Turkish navy frigate on Thursday off Akamas, will continue operations, Agriculture Minister Nicos Kouyialis said on Sunday.The company that owns the research vessel, Kouyialis told the Cyprus News Agency, was hired by his ministry to collect information on its behalf concerning dolphins and whales in the area.He added that it was forced by a Turkish frigate to change its course.The vessel will continue its research programme which is expected to be completed within the coming days, Kouyialis said. The research is part of a programme of the fisheries department aiming to collect information on the marine area of Cyprus.“It is within our obligations as an EU member-state to collect information concerning the sea,”Kouyialis said.He added that the issue was being handled by the foreign affairs ministry.On Thursday, a Turkish navy frigate approached the Cyprus-flagged vessel some 12 miles off the Akamas coast on the western tip of the island. The frigate reportedly contacted the vessel and demanded that it abandoned the area because it was violating Turkish territory.Government spokesman Nicos Christodoulides had said the Republic will undertake all the appropriate actions with international organisations and foreign governments.Turkey claims it has rights in the area and has sought to disrupt natural gas exploration carried out by international energy companies who won concessions in the EEZ.Three oil majors were involved in the third hydrocarbon licensing round – ExxonMobil, ENI, and Total.You May LikePopularEverythingColorado Mom Adopted Two Children, Months Later She Learned Who They Really ArePopularEverythingUndoLivestlyChip And Joanna’s $18M Mansion Is Perfect, But It’s The Backyard Everyone Is Talking AboutLivestlyUndoModernizeIf Your Home Has Old Roofing, Read ThisModernizeUndo Pensioner dies after crash on Paphos-Polis roadUndoCypriot tycoon launches ‘Bank of Cannabis’UndoThree arrested in connection with hotel theftsUndoby Taboolaby Taboola
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